If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Protein Tyrosine Phosphatases Medicine & Life Sciences
Non-Receptor Type 11 Protein Tyrosine Phosphatase Medicine & Life Sciences
Mutation Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Tyrosine Medicine & Life Sciences
Embryonic Stem Cells Medicine & Life Sciences
SH2 Domain-Containing Protein Tyrosine Phosphatases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2002 2020

Noonan Syndrome
Stem Cell Niche
Germ-Line Mutation
Leukemia
Mutation

Metabolic regulation of hematopoietic stem cell function

Qu, C.

National Institutes of Health

9/15/115/31/20

Project: Research projectResearch Project

Hematopoietic Stem Cells
Cell Lineage
Energy Metabolism
Hematopoiesis
Phosphoric Monoester Hydrolases

Targeting metabolism in leukemic stem cells

Qu, C.

National Institutes of Health

4/1/143/31/16

Project: Research projectExploratory/Developmental Grants

Stem Cells
Hematopoietic Stem Cells
Acute Myeloid Leukemia
Cell Differentiation
Embryonic Stem Cells

Targeting SHP2 Phosphatase for Hematologic Malignancies in Noonan Syndrome

Qu, C.

National Institutes of Health

9/23/118/31/14

Project: Research projectExploratory/Developmental Grants

Non-Receptor Type 11 Protein Tyrosine Phosphatase
Noonan Syndrome
Hematologic Neoplasms
Leukemia
Juvenile Myelomonocytic Leukemia

Research Output 1996 2018

6 Citations

Factor XII and uPAR upregulate neutrophil functions to influence wound healing

Stavrou, E. X., Fang, C., Bane, K. L., Long, A. T., Naudin, C., Kucukal, E., Gandhi, A., Brett-Morris, A., Mumaw, M. M., Izadmehr, S., Merkulova, A., Reynolds, C. C., Alhalabi, O., Nayak, L., Yu, W. M., Qu, C-K., Meyerson, H. J., Dubyak, G. R., Gurkan, U., Nieman, M. T. & 3 othersSen Gupta, A., Renné, T. & Schmaier, A. H., Mar 1 2018, In : Journal of Clinical Investigation. 128, 3, p. 944-959 16 p.

Research output: Contribution to journalArticle

Factor XII
Wound Healing
Neutrophils
Up-Regulation
Inflammation
2 Citations

Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner

Zheng, H., Yu, W. M., Waclaw, R. R., Kontaridis, M. I., Neel, B. G. & Qu, C-K., Mar 20 2018, In : Science Signaling. 11, 522, eaao1591.

Research output: Contribution to journalArticle

Non-Receptor Type 11 Protein Tyrosine Phosphatase
Gene encoding
Hydrocephalus
Tyrosine
Mutation

Germline mutations in the bone marrow microenvironment and dysregulated hematopoiesis

Miller, L. H., Qu, C-K. & Pauly, M., Oct 1 2018, In : Experimental Hematology. 66, p. 17-26 10 p.

Research output: Contribution to journalReview article

Germ-Line Mutation
Hematopoiesis
Bone Marrow
Hematopoietic Stem Cells
Leukemia

Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development

Zheng, H., Yu, W. M., Shen, J., Kang, S., Hambardzumyan, D., Li, J. Y., Shen, Y., Kenney, A. M., Chen, J. & Qu, C-K., Oct 10 2018, In : Science Advances. 4, 10, aat2681.

Research output: Contribution to journalArticle

Neural Stem Cells
Carbohydrates
Cell Cycle Checkpoints
Pyruvic Acid
Knockout Mice
5 Citations

The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer

Jin, L., Chun, J., Pan, C., Kumar, A., Zhang, G., Ha, Y., Li, D., Alesi, G. N., Kang, Y., Zhou, L., Yu, W. M., Magliocca, K. R., Khuri, F. R., Qu, C-K., Metallo, C., Owonikoko, T. K. & Kang, S., Jan 4 2018, In : Molecular Cell. 69, 1, p. 87-99.e7

Research output: Contribution to journalArticle

Anoikis
Pleomorphic Adenoma
Glutamate Dehydrogenase
AMP-Activated Protein Kinases
Lung Neoplasms