George B. Hoppe, PhD

Former affiliation
  • 2019 Citations
  • 22 h-Index
19942018
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Research Output 1994 2018

  • 2019 Citations
  • 22 h-Index
  • 37 Article
  • 1 Conference contribution

3-hydroxypyruvate destabilizes hypoxia inducible factor and induces angiostasis

Singh, C., Sharma, A., Hoppe, G. B., Song, W., Bolok, Y. & Sears, J. E., Jul 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 8, p. 3440-3448 9 p.

Research output: Contribution to journalArticle

Pyruvic Acid
Hyperoxia
Endothelial Cells
Serine
Retina
18 Citations

Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity

Hoppe, G. B., Yoon, S., Gopalan, B., Savage, A. R., Brown, R., Case, K., Vasanji, A., Chan, E. R., Silver, R. B. & Sears, J. E., May 3 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 18, p. E2516-E2525

Research output: Contribution to journalArticle

Retinopathy of Prematurity
Pharmacology
Oxygen
Hypoxia-Inducible Factor 1
Liver
14 Citations

Proangiogenic properties of thrombospondin-4

Muppala, S., Frolova, E., Xiao, R., Krukovets, I., Yoon, S., Hoppe, G. B., Vasanji, A., Plow, E. F. & Stenina-Adognravi, O., Sep 28 2015, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 35, 9, p. 1975-1986 12 p.

Research output: Contribution to journalArticle

Endothelial Cells
Thrombospondin 1
Blood Vessels
Cartilage Oligomeric Matrix Protein
thrombospondin 4
5 Citations

Inducing a visceral organ to protect a peripheral capillary bed: Stabilizing hepatic HIF-1α prevents oxygen-induced retinopathy

Hoppe, G. B., Lee, T. J., Yoon, S., Yu, M., Peachey, N. S., Rayborn, M., Zutel, M. J., Trichonas, G., Au, J. & Sears, J. E., 2014, In : American Journal of Pathology. 184, 6, p. 1890-1899 10 p.

Research output: Contribution to journalArticle

Oxygen
Liver
Knockout Mice
Retina
Electroretinography
14 Citations

Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy in the rat 50/10 model

Trichonas, G., Lee, T. J., Hoppe, G. B., Au, J. & Sears, J. E., 2013, In : Investigative Ophthalmology and Visual Science. 54, 7, p. 4919-4926 8 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Hyperoxia
Oxygen
Intraperitoneal Injections
Blood Vessels