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  • 9 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Neurons Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Oxidative stress Chemical Compounds
Mitochondrial Dynamics Medicine & Life Sciences
Mitochondria Medicine & Life Sciences

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Projects 2006 2021

Molecular Mechanisms Underlying Mitochondrial Dynamics Abnormalities in Alzheimer Disease

Zhu, X.

National Institutes of Health

9/30/166/30/21

Project: Research projectMulti-Year Funded Research Project Grant

Mitochondrial Dynamics
Alzheimer Disease
Calcium Signaling
Calcium
Neurons

Epigenomic Mechanism of Parkinson's Disease

Zhu, X.

National Institutes of Health

9/20/138/31/16

Project: Research projectResearch Project

Wnt Signaling Pathway
Epigenomics
Parkinson Disease
DNA Methylation
Brain
Mitochondrial Dynamics
Transgenic Mice
Hippocampus
Mitochondria
Organelles

Research Output 1998 2018

Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior

Huang, X., Xiaokaiti, Y., Yang, J., Pan, J., Li, Z., Luria, V., Li, Y., Song, G., Zhu, X., Zhang, H. T., O'Donnell, J. M. & Xu, Y., Dec 1 2018, In : Neuropharmacology. 143, p. 176-185 10 p.

Research output: Contribution to journalArticle

Oxidoreductases
Anxiety
Depression
Oxidative Stress
Brain-Derived Neurotrophic Factor
1 Citations

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease

He, L., Jiang, Y., Liu, K., Gomez-Murcia, V., Ma, X., Torrecillas, A., Chen, Q., Zhu, X., Lesnefsky, E., Gomez-Fernandez, J. C., Xu, B. & Zhang, S., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 777-790 14 p.

Research output: Contribution to journalArticle

Neuroprotective Agents
Diosgenin
Alzheimer Disease
Membranes
Mitochondria
2 Citations

Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex

Jiang, S., Nandy, P., Wang, W., Ma, X., Hsia, J., Wang, C., Wang, Z., Niu, M., Siedlak, S. L., Torres, S., Fujioka, H., Xu, Y., Lee, H., Perry, G., Liu, J. & Zhu, X., Feb 1 2018, In : Molecular Neurodegeneration. 13, 1, 5.

Research output: Contribution to journalArticle

Mitochondrial Dynamics
Hippocampus
Alzheimer Disease
Oxidative Stress
Mitochondria
9 Citations

A conserved retromer sorting motif is essential for mitochondrial DLP1 recycling by vps35 in parkinson's disease model

Wang, W., Ma, X., Zhou, L., Liu, J. & Zhu, X., Feb 15 2017, In : Human Molecular Genetics. 26, 4, p. 781-789 9 p.

Research output: Contribution to journalArticle

Recycling
Parkinson Disease
Mitochondrial Dynamics
Peptides
Mutation
2 Citations

Consequences of RNA oxidation on protein synthesis rate and fidelity: Implications for the pathophysiology of neuropsychiatric disorders

Nunomura, A., Lee, H., Zhu, X. & Perry, G., Oct 15 2017, In : Biochemical Society Transactions. 45, 5, p. 1053-1066 14 p.

Research output: Contribution to journalReview article

RNA
Oxidation
Messenger RNA
Proteins
Guanosine

Press/Media

So Immature—Aβ Stymies Mitochondrial Protein Processing

Xiongwei Zhu

8/28/14

1 item of media coverage

Press/Media: Press / Media

Top Specialists in Alzheimer Disease

Xiongwei Zhu

11/14/13

1 item of media coverage

Press/Media: Press / Media