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The IU/JAX Alzheimer's Disease Precision Models Center

Lamb, B. T.

National Institutes of Health

9/30/165/31/21

Project: Research projectSpecialized Center--Cooperative Agreements

Alzheimer Disease
Dementia
Animal Disease Models
Drug Industry
Neuroimaging

Molecular Mechanisms Underlying Mitochondrial Dynamics Abnormalities in Alzheimer Disease

Zhu, X.

National Institutes of Health

9/30/166/30/21

Project: Research projectMulti-Year Funded Research Project Grant

Mitochondrial Dynamics
Alzheimer Disease
Calcium Signaling
Calcium
Neurons

Ubiquitination and Deubiquitination of c-Myc in Glioblastoma

Bao, S.

National Institutes of Health

9/30/166/30/21

Project: Research projectResearch Project

Ubiquitination
Glioblastoma
Glioma
Stem Cells
Ubiquitin-Specific Proteases
Cell death
Nanoparticles
Oxygen
Oxidative stress
Antioxidants
Safety
Delivery of Health Care
Quality of Health Care
Nurses
Education
Self Care
Caregivers
Health
Mental Health
Education
Positive Transcriptional Elongation Factor B
RNA Polymerase II
Phosphotransferases
Phosphorylation
In Vitro Techniques

Cancer Imaging and Therapy Platform

Wilson, D. L.

National Institutes of Health

9/20/168/31/17

Project: Research projectSmall Business Technology Transfer (STTR) Grants - Phase I

Imaging techniques
Histology
Tumors
Fluorescence
Animals
Cytoplasmic and Nuclear Receptors
Lakes
Posters
Neoplasms
Nonprofit Organizations

Regenerative nanopharmacotherapy for small abdominal aortic aneurysms

Ramamurthi, A.

National Institutes of Health

9/15/168/31/17

Project: Research projectHigh Priority, Short Term Project Award

Abdominal Aortic Aneurysm

Structure-Guided Analysis of Mechanisms of AT1R Functions

Karnik, S. S.

National Institutes of Health

9/15/168/31/17

Project: Research projectHigh Priority, Short Term Project Award

Ligands
Filamins
Cell Adhesion
Proteins
Cardiovascular Physiological Phenomena
Regain
Restoration
Skin
Signal processing
Atherosclerotic Plaques
Integrins
Positron-Emission Tomography
Transient Ischemic Attack
Rupture

The Case Medical Student Summer Research Program (MSSRP)

Cominelli, F. & Pizarro, T. T.

National Institutes of Health

9/9/168/31/21

Project: Research projectNRSA Short -Term Research Training

Medical Students
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Mentors
Students
Cost Sharing

Reducing Sedentary Time in Patients with Heart Failure (ReST-HF)

Boxer, R. S.

National Institutes of Health

9/1/165/31/18

Project: Research projectExploratory/Developmental Grants

Heart Failure
Exercise
Cardiomyopathies
Motor Activity
Teaching Materials
Mass spectrometry
Electric network analysis
Testing
Cell signaling
Genes
Technology
Proteins
Equipment and Supplies
Proteomics
Paraffin

Regulatory Mechanisms of Glycoprotein Sialylation

Cobb, B. A.

National Institutes of Health

9/1/168/31/20

Project: Research projectResearch Project

Glycomics
Glycoproteins
Immunoglobulin G
Glycosylation
Polysaccharides

Cancer Stem Cell (CSC) 2016 Conference

Gerson, S. L.

National Institutes of Health

9/1/168/31/17

Project: Research projectConference

Neoplastic Stem Cells
Disabled Persons
Cell Biology
Neoplasms
Myelodysplastic Syndromes
Genes
Haploinsufficiency
RNA
Mutation

Reversal of HIV latency by METH and Inflammation

Karn, J.

National Institutes of Health

9/1/166/30/21

Project: Research projectResearch Project

Methamphetamine
HIV
Inflammation
Microglia
Street Drugs
Proteome
Thrombosis
Blood Platelets
Ubiquitin-Specific Proteases
Ubiquitin

Role of Zinc in HIV inflammation

McComsey, G. A.

National Institutes of Health

9/1/168/31/18

Project: Research projectExploratory/Developmental Grants

Zinc
HIV
Inflammation
Innate Immunity
Monocytes

Cell-based Therapy in RA: Proof of Concept

Singer, N. G. & Lazarus, H. M.

National Institutes of Health

9/1/168/31/19

Project: Research projectExploratory/Developmental Grants

Cell- and Tissue-Based Therapy
Mesenchymal Stromal Cells
Inflammation
Safety
Methotrexate

Hibbs -Association Between Intermittent Hypoxia and Later Respiratory Morbidity

Hibbs, A. M.

National Institutes of Health

9/1/166/30/21

Project: Research projectResearch Project--Cooperative Agreements

Anoxia
Morbidity
Respiratory Sounds
Premature Infants
Oxidative Stress

Clinical Evaluation of Point of Care Raman Analysis for Diagnosis of Gout

Singer, N. G.

National Institutes of Health

9/1/168/31/17

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

Gout
Equipment and Supplies
Polarization Microscopy
Synovial Fluid
Chondrocalcinosis
Asthma
Cystic Fibrosis
Epithelial Cells
Clinical Trials
Cell Culture Techniques

Cellular model for personalized CFTR-directed therapeutics

Cotton, C. U.

National Institutes of Health

8/22/162/28/18

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Nose
Epithelial Cells
Air Filters

Preclinical Study of IL-27-Conditioned Tregs to Treat GvHD

Min, B.

National Institutes of Health

8/19/167/31/18

Project: Research projectExploratory/Developmental Grants

Interleukin-27
Inflammation
Immunosuppression
T-Lymphocytes
Regulatory T-Lymphocytes

Kinase Dependent Chemotherapy Resistance Mechanisms in Small Cell Lung Cancer

National Institutes of Health

8/19/167/31/18

Project: Research projectExploratory/Developmental Grants

Small Cell Lung Carcinoma
Phosphotransferases
Drug Therapy
Computational Biology
Genomics

Repurposing Anti-cancer Drugs to Prevent Growth of Osteosarcoma Metastases

Greenfield, E. M.

National Institutes of Health

8/18/167/31/18

Project: Research projectExploratory/Developmental Grants

Tumors
Bone
Chemotherapy
Collagen
Screening
Cerebellum
Anoxia
Ischemia
Inflammation
Lipids

Center for Modeling Tumor Cell Migration Mechanics

Rosenfeld, S. S.

National Institutes of Health

8/17/167/31/21

Project: Research projectSpecialized Center--Cooperative Agreements

Cell Movement
Neoplasms
Tumor Microenvironment
Drug Resistance
Computer Simulation

Imaging Liver Cancer Proliferation

Lee, Z. & Saunthararajah, Y.

National Institutes of Health

8/15/167/31/21

Project: Research projectResearch Project

Liver
Polyethylene terephthalates
Imaging techniques
Glucose
Substrates

Casein kinase 2 signaling in axonal injury

Baltan, S.

National Institutes of Health

8/15/167/31/18

Project: Research projectExploratory/Developmental Grants

Casein Kinase II
Wounds and Injuries
Oligodendroglia
Ischemia
Oxygen
Noonan Syndrome
Stem Cell Niche
Germ-Line Mutation
Mutation
Leukemia
Long Noncoding RNA
Life Cycle Stages
HIV
T-Lymphocytes
Biogenesis
HIV-1
HIV
Brain
Genes
Virus Latency

Roles of SOXC proteins in osteogenic cells

Lefebvre, V. M.

National Institutes of Health

7/21/166/30/21

Project: Research projectResearch Project

Stem Cells
Proteins
Genes
Bone and Bones
Bone Diseases
Urinary Incontinence
Obesity
Type 2 Diabetes Mellitus
Diet
Urinary Bladder

The Southeastern Consortium for Microscopy of MacroMolecular Machines

Stewart, P. L.

National Institutes of Health

7/18/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Electrons
Microscopic examination
Detectors
Image recording
Membrane structures

CryoEM Data Collection Facility Consortium at NCMI

Stewart, P. L.

National Institutes of Health

7/15/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Electron microscopy
Tomography
Microscopes
Imaging techniques
Macromolecules
Pumps
Testing
Biocompatibility
Specifications
Experiments

Glioblastoma stem cell-derived pericytes and cancer invasion

Bao, S.

National Institutes of Health

7/15/164/30/21

Project: Research projectResearch Project

Pericytes
Neoplastic Stem Cells
Glioblastoma
Neoplasms
Glioma

West/Midwest Consortium for High-Resolution Cryo Electron Microscopy

Stewart, P. L.

National Institutes of Health

7/11/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Electron microscopy
Imaging techniques
Microscopes
Reservation systems
Nanosystems

A novel T-cell subset able to kill relapsed cancers

Yi, Q.

National Institutes of Health

7/1/166/30/21

Project: Research projectResearch Project

T-Lymphocyte Subsets
Neoplasms
Antigens
Immunotherapy
Interleukin-9
Exercise
Bone and Bones
Bone Density
Veterans
Osteoporosis
Resveratrol
Transplantation (surgical)
Micelles
Nanoparticles
Immune system

Diet, Gut Microbiota, and Heart Failure

Tang, W. (. H. & Hazen, S. A.

National Institutes of Health

7/1/164/30/20

Project: Research projectResearch Project

Microbiota
Heart Failure
Diet
Oxides
Food