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Ubiquitination and Deubiquitination of c-Myc in Glioblastoma

Bao, S.

National Institutes of Health

9/30/166/30/21

Project: Research projectResearch Project

Ubiquitination
Glioblastoma
Glioma
Stem Cells
Ubiquitin-Specific Proteases
Nanoparticles
Catalase
Superoxide Dismutase
Retinitis Pigmentosa
Photoreceptor Cells

The IU/JAX Alzheimer's Disease Precision Models Center

National Institutes of Health

9/30/165/31/21

Project: Research projectSpecialized Center--Cooperative Agreements

Alzheimer Disease
Dementia
Animal Disease Models
Drug Industry
Neuroimaging

Molecular Mechanisms Underlying Mitochondrial Dynamics Abnormalities in Alzheimer Disease

Zhu, X.

National Institutes of Health

9/30/166/30/21

Project: Research projectMulti-Year Funded Research Project Grant

Mitochondrial Dynamics
Alzheimer Disease
Calcium Signaling
Calcium
Neurons
Self Care
Caregivers
Health
Mental Health
Education
Positive Transcriptional Elongation Factor B
RNA Polymerase II
Phosphotransferases
Phosphorylation
In Vitro Techniques
Hand Strength
Orphaned Children
Posture
Quality of Life
Outcome Assessment (Health Care)

The Case Medical Student Summer Research Program (MSSRP)

Cominelli, F. & Pizarro, T. T.

National Institutes of Health

9/9/168/31/21

Project: Research projectNRSA Short -Term Research Training

Medical Students
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Mentors
Students
Cost Sharing

Role of Zinc in HIV inflammation

McComsey, G. A.

National Institutes of Health

9/1/168/31/18

Project: Research projectExploratory/Developmental Grants

Zinc
HIV
Inflammation
Innate Immunity
Monocytes
Proteome
Thrombosis
Blood Platelets
Ubiquitin-Specific Proteases
Ubiquitin

Regulatory Mechanisms of Glycoprotein Sialylation

Cobb, B. A.

National Institutes of Health

9/1/168/31/20

Project: Research projectResearch Project

Glycomics
Glycoproteins
Immunoglobulin G
Glycosylation
Polysaccharides

Reversal of HIV latency by METH and Inflammation

Karn, J.

National Institutes of Health

9/1/166/30/21

Project: Research projectResearch Project

Methamphetamine
HIV
Inflammation
Microglia
Street Drugs

Reducing Sedentary Time in Patients with Heart Failure (ReST-HF)

National Institutes of Health

9/1/165/31/18

Project: Research projectExploratory/Developmental Grants

Heart Failure
Exercise
Cardiomyopathies
Motor Activity
Teaching Materials
Myelodysplastic Syndromes
Genes
Haploinsufficiency
RNA
Mutation

Cell-based Therapy in RA: Proof of Concept

Singer, N. G. & Lazarus, H. M.

National Institutes of Health

9/1/168/31/19

Project: Research projectExploratory/Developmental Grants

Cell- and Tissue-Based Therapy
Mesenchymal Stromal Cells
Inflammation
Safety
Methotrexate
Mass spectrometry
Electric network analysis
Testing
Cell signaling
Genes

NEI CENTER CORE GRANT FOR VISION RESEARCH

Hagstrom, S. A. & Dupps, W. (. J.

National Institutes of Health

9/1/168/31/21

Project: Research projectCenter Core Grants

Technology
Proteins
Equipment and Supplies
Proteomics
Paraffin

Hibbs -Association Between Intermittent Hypoxia and Later Respiratory Morbidity

Hibbs, A. M.

National Institutes of Health

9/1/166/30/21

Project: Research projectResearch Project--Cooperative Agreements

Anoxia
Morbidity
Respiratory Sounds
Premature Infants
Oxidative Stress
Asthma
Cystic Fibrosis
Epithelial Cells
Clinical Trials
Cell Culture Techniques

Cellular model for personalized CFTR-directed therapeutics

Cotton, C. U.

National Institutes of Health

8/22/162/28/18

Project: Research projectSmall Business Innovation Research Grants (SBIR) - Phase I

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Nose
Epithelial Cells
Air Filters

Kinase Dependent Chemotherapy Resistance Mechanisms in Small Cell Lung Cancer

National Institutes of Health

8/19/167/31/18

Project: Research projectExploratory/Developmental Grants

Small Cell Lung Carcinoma
Phosphotransferases
Drug Therapy
Computational Biology
Genomics

Preclinical Study of IL-27-Conditioned Tregs to Treat GvHD

Min, B.

National Institutes of Health

8/19/167/31/18

Project: Research projectExploratory/Developmental Grants

Interleukin-27
Inflammation
Immunosuppression
T-Lymphocytes
Regulatory T-Lymphocytes

Repurposing Anti-cancer Drugs to Prevent Growth of Osteosarcoma Metastases

Greenfield, E. M.

National Institutes of Health

8/18/167/31/18

Project: Research projectExploratory/Developmental Grants

Osteosarcoma
Neoplasm Metastasis
Neoplasms
Bone and Bones
Lung
Cerebellum
Anoxia
Ischemia
Inflammation
Lipids

Center for Modeling Tumor Cell Migration Mechanics

Rosenfeld, S. S.

National Institutes of Health

8/17/167/31/21

Project: Research projectSpecialized Center--Cooperative Agreements

Cell Movement
Neoplasms
Tumor Microenvironment
Drug Resistance
Computer Simulation

Imaging Liver Cancer Proliferation

Lee, Z. & Saunthararajah, Y.

National Institutes of Health

8/15/167/31/21

Project: Research projectResearch Project

Liver Neoplasms
Hepatocellular Carcinoma
Liver
Deoxycytidine Kinase
Cytidine Deaminase

Casein kinase 2 signaling in axonal injury

Baltan, S.

National Institutes of Health

8/15/167/31/18

Project: Research projectExploratory/Developmental Grants

Casein Kinase II
Wounds and Injuries
Oligodendroglia
Ischemia
Oxygen
Noonan Syndrome
Stem Cell Niche
Germ-Line Mutation
Mutation
Leukemia
Long Noncoding RNA
Life Cycle Stages
HIV
T-Lymphocytes
Biogenesis
HIV-1
HIV
Brain
Genes
Virus Latency

Roles of SOXC proteins in osteogenic cells

Lefebvre, V. M.

National Institutes of Health

7/21/166/30/21

Project: Research projectResearch Project

Stem Cells
Proteins
Genes
Bone and Bones
Bone Diseases
Urinary Incontinence
Obesity
Type 2 Diabetes Mellitus
Diet
Urinary Bladder

The Southeastern Consortium for Microscopy of MacroMolecular Machines

Stewart, P. L.

National Institutes of Health

7/18/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Electrons
Acromion
Biophysics
Antimetabolites
Dibenzoxepins

Glioblastoma stem cell-derived pericytes and cancer invasion

Bao, S.

National Institutes of Health

7/15/164/30/21

Project: Research projectResearch Project

Pericytes
Neoplastic Stem Cells
Glioblastoma
Neoplasms
Glioma

CryoEM Data Collection Facility Consortium at NCMI

Stewart, P. L.

National Institutes of Health

7/15/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

Electron microscopy
Tomography
Microscopes
Imaging techniques
Macromolecules
Heart-Assist Devices
Hemolysis
Thrombosis
Heart Failure
Equipment and Supplies

West/Midwest Consortium for High-Resolution Cryo Electron Microscopy

Stewart, P. L.

National Institutes of Health

7/11/166/30/21

Project: Research projectResource-Related Research Projects--Cooperative Agreements

user
staff
instruments
facility
image
Exercise
Bone and Bones
Bone Density
Veterans
Osteoporosis
Selenoproteins
Selenocysteine
Messenger RNA
3' Untranslated Regions
Proteins

Training Program in HIV Cure

Levine, A. D.

National Institutes of Health

7/1/166/30/21

Project: Research projectInstitutional National Research Service Award

HIV
Education
Allergy and Immunology
Medicine
Systems Biology
Neoplasms
Pathology
Telepathology
Observer Variation
Genetic Heterogeneity

A novel T-cell subset able to kill relapsed cancers

Yi, Q.

National Institutes of Health

7/1/166/30/21

Project: Research projectResearch Project

T-Lymphocyte Subsets
Neoplasms
Antigens
Immunotherapy
Interleukin-9
Organ Transplantation
Allografts
Micelles
Nanoparticles
Immune System
S-Nitrosothiols
Oxygen
Hemoglobins
Erythrocytes
Wounds and Injuries

Diet, Gut Microbiota, and Heart Failure

Tang, W. (. H.

National Institutes of Health

7/1/164/30/20

Project: Research projectResearch Project

Microbiota
Heart Failure
Diet
Oxides
Food
Genetic Therapy
Atrial Fibrillation
Genes
Paintings
Safety

Combating persistent viral infections using cell specific therapies

Popkin, D.

National Institutes of Health

7/1/166/30/20

Project: Research projectNon-HHS Research Projects

Cell- and Tissue-Based Therapy
Infection
Dendritic Cells
Lymphocytic choriomeningitis virus
Antigen-Presenting Cells

Identification of Glucose Transporter 3 Inhibitors for Glioblastoma Treatment

National Institutes of Health

6/15/163/31/18

Project: Research projectExploratory/Developmental Grants

Neoplastic Stem Cells
Glioblastoma
Brain Neoplasms
Glucose
Neoplasms
Pedigree
Cluster Analysis
Haplotypes
Datasets
Recombinant DNA