Find Research Outputs

2018

Androgen Deprivation Fortified

Mendiratta, P. & Garcia, J. A., Apr 1 2018, In : International Journal of Radiation Oncology Biology Physics. 100, 5, p. 1091-1094 4 p.

Research output: Contribution to journalLetter

deprivation
Androgens
6 Citations

Androgen-induced immunosuppression

Bupp, M. R. G. & Jorgensen, T. N., Apr 17 2018, In : Frontiers in Immunology. 9, APR, 794.

Research output: Contribution to journalReview article

Gonadal Steroid Hormones
Immunosuppression
Androgens
Androgen Receptors
Systemic Lupus Erythematosus
2 Citations

An eQTL Landscape of Kidney Tissue in Human Nephrotic Syndrome

Nephrotic Syndrome Study Network (NEPTUNE), Aug 2 2018, In : American journal of human genetics. 103, 2, p. 232-244 13 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Nephrotic Syndrome
Kidney
Transcriptome
Genome-Wide Association Study
1 Citations

An evaluation of the pharmacotherapy for interstitial cystitis

Giusto, L. L., Zahner, P. M. & Shoskes, D. A., Jul 3 2018, In : Expert Opinion on Pharmacotherapy. 19, 10, p. 1097-1108 12 p.

Research output: Contribution to journalReview article

Interstitial Cystitis
Drug Therapy
Urinary Bladder
Therapeutics
Guidelines

A new bioluminescent imaging technology for studying oxidative stress in the testis and its impacts on fertility

Ma, Q., Shao, H., Feng, Y., Zhang, L., Li, P., Hu, X., Ma, Z., Lou, H., Zeng, X. & Luo, G., Aug 20 2018, In : Free Radical Biology and Medicine. 124, p. 51-60 10 p.

Research output: Contribution to journalArticle

Male Infertility
Acetaminophen
Fertility
Testis
Oxidative Stress

A New Composite Eyeball-Periorbital Transplantation Model in Humans: An Anatomical Study in Preparation for Eyeball Transplantation

Siemionow, M., Bozkurt, M., Zor, F., Kulahci, Y., Uygur, S., Ozturk, C., Djohan, R. & Papay, F., Apr 1 2018, In : Plastic and reconstructive surgery. 141, 4, p. 1011-1018 8 p.

Research output: Contribution to journalArticle

Transplantation
Indocyanine Green
Methylene Blue
Osteotomy
Cadaver

A new measure for end of life planning, preparation, and preferences in Huntington disease: HDQLIFE end of life planning

HDQLIFE Site Investigators and Coordinators, Jan 1 2018, In : Journal of Neurology. 265, 1, p. 98-107 10 p.

Research output: Contribution to journalArticle

Huntington Disease
Psychometrics
Statistical Factor Analysis
Hospice Care
Terminal Care
1 Citations

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7

Subramanian, G., Kuzmanovic, T., Zhang, Y., Peter, C. B., Veleeparambil, M., Chakravarti, R., Sen, G. & Chattopadhyay, S., Jan 1 2018, In : PLoS Pathogens. 14, 1, e1006877.

Research output: Contribution to journalArticle

Autophagy
Interferons
Antiviral Agents
Sendai virus
Genes

A new STAT3 function: pH regulation

Wang, Y. & Stark, G. S., Jan 1 2018, (Accepted/In press) In : Cell Research.

Research output: Contribution to journalArticle

A new technique for hepatic parenchymal transection using an articulating bipolar 5 cm radiofrequency device: results from the first 100 procedures

Takahashi, H., Akyuz, M., Aksoy, E., Aucejo, F., Quintini, C., Miller, C., Fung, J. & Berber, E., Jan 1 2018, (Accepted/In press) In : HPB.

Research output: Contribution to journalArticle

Equipment and Supplies
Liver
Alligators and Crocodiles
Research Ethics Committees
Hepatectomy

A New Year's transition and looking forward

Mandell, B., Jan 1 2018, In : Cleveland Clinic journal of medicine. 85, 1, p. 6-7 2 p.

Research output: Contribution to journalEditorial

An expedient synthesis of CMF-019: (s)-5-methyl-3-{1-(pentan-3-yl)-2-(thiophen-2-ylmethyl)-1h-benzo[d]imidazole-5-carboxamido}hexanoic acid, a potent apelin receptor (APJ) agonist

Trifonov, L., Afri, M., Palczewski, K., Korshin, E. E. & Gruzman, A., Jan 1 2018, In : Medicinal Chemistry. 14, 7, p. 688-694 7 p.

Research output: Contribution to journalArticle

Salts
Peptidomimetics
Thiophenes
Benzoates
G-Protein-Coupled Receptors

Angiotensin II increases angiogenesis by NF-kB–mediated transcriptional activation of angiogenic factor AGGF1

Si, W., Xie, W., Deng, W., Xiao, Y., Karnik, S. S., Xu, C., Chen, Q. & Wang, Q. K., Sep 1 2018, In : FASEB Journal. 32, 9, p. 5051-5062 12 p.

Research output: Contribution to journalArticle

NF-kappa B
Angiogenesis Inducing Agents
Angiotensin II
Chemical activation
Small Interfering RNA
1 Citations
Bridge decks
Snow
Piles
Melting
Phase change materials

An in-situ photocrosslinking microfluidic technique to generate non-spherical, cytocompatible, degradable, monodisperse alginate microgels for chondrocyte encapsulation

Wang, S., Bruning, A., Jeon, O., Long, F., Alsberg, E. & Choi, C. K., Jan 1 2018, In : Biomicrofluidics. 12, 1, 014106.

Research output: Contribution to journalArticle

Microfluidics
Alginate
crosslinking
Chondrocytes
Encapsulation
12 Citations

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

Atlases
Genes
Genome
Survival
Neoplasms

An integrative review of the literature on in-hospital worsening heart failure

Albert, N. M., Jan 1 2018, (Accepted/In press) In : Heart and Lung.

Research output: Contribution to journalArticle

Heart Failure
Incidence
Length of Stay
Therapeutics
Databases

An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

Fatkhullina, A. R., Peshkova, I. O., Dzutsev, A., Aghayev, T., McCulloch, J. A., Thovarai, V., Badger, J. H., Vats, R., Sundd, P., Tang, H. Y., Kossenkov, A. V., Hazen, S. A., Trinchieri, G., Grivennikov, S. I. & Koltsova, E. K., Nov 20 2018, In : Immunity. 49, 5, p. 943-957.e9

Research output: Contribution to journalArticle

Interleukin-23
Microbiota
Myeloid Cells
Atherosclerosis
Homeostasis

An introduction to the Duchenne muscular dystrophy care considerations

Ward, L. M. & Birnkrant, D. J., Oct 1 2018, In : Pediatrics. 142, p. S1-S4

Research output: Contribution to journalArticle

Duchenne Muscular Dystrophy

Anisocytosis and leukocytosis are independently related to survival after transcatheter aortic valve replacement

Attizzani, G. F., Al-Kindi, S. G., Dalton, J. E., Alkhalil, A., DeCicco, A., Mayuga, M., Funderburg, N. T., Blackstone, E. H., Parikh, S. A., Longenecker, C. T., Lederman, M. M., Simon, D. I., Costa, M. A. & Zidar, D., Apr 1 2018, In : Journal of Cardiovascular Medicine. 19, 4, p. 191-194 4 p.

Research output: Contribution to journalLetter

Leukocytosis
Transcatheter Aortic Valve Replacement

A nitinol-actuated worm robot bends for turning and climbing obstacles

Andersen, K. B., Kandhari, A., Chiel, H., Quinn, R. D. & Daltorio, K. A., Jan 1 2018, Biomimetic and Biohybrid Systems - 7th International Conference, Living Machines 2018, Proceedings. Springer Verlag, p. 6-10 5 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 10928 LNAI).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Worm
Locomotion
Robot
Robots
Form Factors
2 Citations

An LC–MS/MS method for simultaneous determination of curcumin, curcumin glucuronide and curcumin sulfate in a phase II clinical trial

Kunati, S. R., Yang, S., William, B. M. & Xu, Y., Jul 15 2018, In : Journal of Pharmaceutical and Biomedical Analysis. 156, p. 189-198 10 p.

Research output: Contribution to journalArticle

Phase II Clinical Trials
Curcumin
Sulfates
Plasma (human)
formic acid

A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-β-lactamase SPS-1

Cheng, Z., Vanpelt, J., Bergstrom, A., Bethel, C., Katko, A., Miller, C., Mason, K., Cumming, E., Zhang, H., Kimble, R. L., Fullington, S., Bretz, S. L., Nix, J. C., Bonomo, R. A., Tierney, D. L., Page, R. C. & Crowder, M. W., Sep 4 2018, In : Biochemistry. 57, 35, p. 5218-5229 12 p.

Research output: Contribution to journalArticle

Zinc Compounds
Cobalt compounds
Spectroscopic analysis
beta-Lactamases
Metal ions

A nonpump function of sodium iodide symporter in thyroid cancer via cross-talk with PTEN signaling

Feng, F., Yehia, L., Ni, Y., Chang, Y. S., Jhiang, S. M. & Eng, C., Nov 1 2018, In : Cancer Research. 78, 21, p. 6121-6133 13 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Glycosylation
Phosphatidylinositol 3-Kinases
Cytoplasm
Cell Membrane
Anatomy
Learning
Students
Research

A novel, data-driven conceptualization for critical left heart obstruction

Congenital Heart Surgeons’ Society, Oct 1 2018, In : Computer Methods and Programs in Biomedicine. 165, p. 107-116 10 p.

Research output: Contribution to journalArticle

Pathology
Aortic Valve
Cluster analysis
Cluster Analysis
Newborn Infant

A novel approach for integrating AF-SLO and SDOCT imaging data demonstrates the ability to identify early retinal abnormalities in mutant mice and evaluate the effects of genetic and pharmacological manipulation

Bell, B. A., Bonilha, V. L. & Samuels, I. S., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 167-173 7 p. (Advances in Experimental Medicine and Biology; vol. 1074).

Research output: Chapter in Book/Report/Conference proceedingChapter

Streptozocin
Imaging techniques
Chemical analysis

A novel approach to improving utilization of laboratory testing

Zhou, Y., Procop, G. & Riley, J. D., Feb 1 2018, In : Archives of Pathology and Laboratory Medicine. 142, 2, p. 243-247 5 p.

Research output: Contribution to journalArticle

Practice Guidelines
Hemochromatosis
Transferrin
Institutional Practice
Guidelines
1 Citations

A novel class of microRNA-recognition elements that function only within open reading frames

Zhang, K., Zhang, X., Cai, Z., Zhou, J., Cao, R., Zhao, Y., Chen, Z., Wang, D., Ruan, W., Zhao, Q., Liu, G., Xue, Y., Qin, Y., Zhou, B., Wu, L., Nilsen, T. W., Zhou, Y. & Fu, X. D., Jan 1 2018, (Accepted/In press) In : Nature Structural and Molecular Biology.

Research output: Contribution to journalArticle

MicroRNAs
Open Reading Frames
3' Untranslated Regions
Messenger RNA
Gene Silencing

A novel FBN2 mutation cosegregates with congenital contractural arachnodactyly in a five-generation Chinese family

Zhou, S., Wang, F., Dou, Y., Zhou, J., Hao, G., Xu, C., Wang, Q. K., Wang, H. & Wang, P., Aug 1 2018, In : Clinical Case Reports. 6, 8, p. 1612-1617 6 p.

Research output: Contribution to journalArticle

Mutation
Disulfides
Congenital contractural arachnodactyly
Fibrillin-2
1 Citations

A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia

Sakai, H., Hosono, N., Nakazawa, H., Przychodzen, B., Polprasert, C., Carraway, H. E., Sekeres, M., Radivoyevitch, T., Yoshida, K., Sanada, M., Yoshizato, T., Kataoka, K., Nakagawa, M. M., Ueno, H., Nannya, Y., Kon, A., Shiozawa, Y., Takeda, J., Shiraishi, Y., Chiba, K. & 6 othersMiyano, S., Singh, J., Padgett, R. A., Ogawa, S., Maciejewski, J. P. & Makishima, H., Mar 1 2018, In : Leukemia. 32, 3, p. 839-843 5 p.

Research output: Contribution to journalLetter

Phenotype
1 Citations

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles

Mercer, R. C. C., Daude, N., Dorosh, L., Fu, Z. L., Mays, C. E., Gapeshina, H., Wohlgemuth, S. L., Acevedo-Morantes, C. Y., Yang, J., Cashman, N. R., Coulthart, M. B., Pearson, D. M., Joseph, J. T., Wille, H., Safar, J., Jansen, G. H., Stepanova, M., Sykes, B. D. & Westaway, D., Jan 1 2018, In : PLoS Pathogens. 14, 1, e1006826.

Research output: Contribution to journalArticle

Gerstmann-Straussler-Scheinker Disease
Alleles
Transgenic Mice
Mutation
Thermolysin
1 Citations

A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T- and B-cell acute lymphoblastic Leukemias In Vivo

Nguyen, H. A., Su, Y., Zhang, J. Y., Antanasijevic, A., Caffrey, M., Schalk, A. M., Liu, L., Rondelli, D., Oh, A., Mahmud, D. L., Bosland, M. C., Kajdacsy-Balla, A., Peirs, S., Lammens, T., Mondelaers, V., De Moerloose, B., Goossens, S., Schlicht, M. J., Kabirov, K. K., Lyubimov, A. V. & 4 othersMerrill, B. J., Saunthararajah, Y., Van Vlierberghe, P. & Lavie, A., Mar 15 2018, In : Cancer Research. 78, 6, p. 1549-1560 12 p.

Research output: Contribution to journalArticle

Biphenotypic Acute Leukemia
Glutaminase
Asparaginase
Precursor Cell Lymphoblastic Leukemia-Lymphoma
glutamin-(asparagin-)ase
1 Citations

A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L

Drappier, M., Jha, B. K., Stone, S., Elliott, R., Zhang, R., Vertommen, D., Weiss, S. R., Silverman, R. H. & Michiels, T., Apr 1 2018, In : PLoS Pathogens. 14, 4, e1006989.

Research output: Contribution to journalArticle

Theilovirus
Proteins
Murine hepatitis virus
Ankyrin Repeat
Viruses

A novel pH-dependent membrane peptide that binds to EphA2 and inhibits cell migration

Alves, D. S., Westerfield, J. M., Shi, X., Nguyen, V. P., Stefanski, K. M., Booth, K. R., Kim, S., Morrell-Falvey, J., Wang, B., Abel, S. M., Smith, A. W. & Barrera, F. N., Sep 17 2018, In : eLife. 7

Research output: Contribution to journalArticle

Cell Movement
Tumors
Phosphorylation
Membranes
Peptides

A novel prognostic six-CpG signature in glioblastomas

Yin, A. A., Lu, N., Etcheverry, A., Aubry, M., Barnholtz-Sloan, J. S., Zhang, L. H., Mosser, J., Zhang, W., Zhang, X., Liu, Y. H. & He, Y. L., Mar 1 2018, In : CNS Neuroscience and Therapeutics. 24, 3, p. 167-177 11 p.

Research output: Contribution to journalArticle

Glioblastoma
Glioma
CpG Islands
DNA Methylation
Phenotype

A novel single animal motor function tracking system using simple, readily available software

Dona, K. R., Goss-Varley, M., Shoffstall, A. J. & Capadona, J. B., Aug 31 2018, In : Journal of Visualized Experiments. 2018, 138, e57917.

Research output: Contribution to journalArticle

Ladders
Animals
Software
Rats
Microelectrodes
3 Citations

A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration

Chen, Y., Chen, Y., Jastrzebska, B. E., Golczak, M. B., Gulati, S., Tang, H., Seibel, W., Li, X., Jin, H. G., Han, Y., Gao, S., Zhang, J., Liu, X., Heidari-Torkabadi, H., Stewart, P. L., Harte, W. E., Tochtrop, G. P. & Palczewski, K., Dec 1 2018, In : Nature Communications. 9, 1, 1976.

Research output: Contribution to journalArticle

Rod Opsins
Retinal Degeneration
degeneration
Opsins
therapy

A novel synthetic route for high-index faceted iron oxide concave nanocubes with high T2 relaxivity for in vivo MRI applications

Situ-Loewenstein, S. F., Wickramasinghe, S., Abenojar, E. C., Erokwu, B. O., Flask, C. A., Lee, Z. & Samia, A. C. S., May 1 2018, In : Journal of Materials Science: Materials in Medicine. 29, 5, 58.

Research output: Contribution to journalArticle

Iron oxides
Nanoparticles
Magnetic resonance imaging
Anisotropy
Growth

A novel use of the NeuroBlate SideFire probe for minimally invasive disconnection of a hypothalamic hamartoma in a child with gelastic seizures

Wright, J. M., Staudt, M. D., Alonso, A., Miller, J. P. & Sloan, A. E., Mar 1 2018, In : Journal of Neurosurgery: Pediatrics. 21, 3, p. 302-307 6 p.

Research output: Contribution to journalArticle

Laughter
Seizures
Laser Therapy
Anticonvulsants
Electroencephalography

Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants

Natarajan, G., Shankaran, S., Saha, S., Laptook, A., Das, A., Higgins, R., Stoll, B. J., Bell, E. F., Carlo, W. A., D'Angio, C., DeMauro, S. B., Sanchez, P., Van Meurs, K., Vohr, B., Newman, N., Hale, E. & Hibbs, A. M., Jan 1 2018, (Accepted/In press) In : Journal of Pediatrics.

Research output: Contribution to journalArticle

Premature Infants
Gestational Age
Intracranial Hemorrhages
Periventricular Leukomalacia
Chorioamnionitis
1 Citations

Antibody Profiling by Proteome Microarray with Multiplex Isotype Detection Reveals Overlap between Human and Aotus nancymaae Controlled Malaria Infections

Taghavian, O., Jain, A., Joyner, C. J., Ketchum, S., Nakajima, R., Jasinskas, A., Liang, L., Fong, R., King, C. L., Greenhouse, B., Murphy, M., Bailey, J., Galinski, M. R., Barnwell, J. W., Plowe, C. V., Davies, D. H. & Felgner, P. L., Jan 1 2018, In : Proteomics. 18, 2, 1700277.

Research output: Contribution to journalArticle

Proteome
Microarrays
Malaria
Immunoglobulin G
Multiplexing
1 Citations

Antibody receptors steal the sweet spotlight

Oliva, K. D., Cavanaugh, J. M. & Cobb, B. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 10, p. 3490-3491 2 p.

Research output: Contribution to journalArticle

Glycosylation
Fc Receptors
Immunoglobulin G
Polysaccharides
Antibodies

Anti-cancer vaccine therapy for hematologic malignancies: An evolving era

Nahas, M. R., Rosenblatt, J., Lazarus, H. M. & Avigan, D., Jan 1 2018, (Accepted/In press) In : Blood Reviews.

Research output: Contribution to journalArticle

Active Immunotherapy
Cancer Vaccines
Hematologic Neoplasms
Neoplasms
T-Lymphocytes

Anti-CD19 chimeric antigen receptor targeting of CD19 + acute myeloid leukemia

Ma, G., Wang, Y., Ahmed, T., Zaslav, A. L., Hogan, L., Avila, C., Wada, M. & Salman, H. S., Jan 1 2018, In : Leukemia Research Reports. 9, p. 42-44 3 p.

Research output: Contribution to journalArticle

CD19 Antigens
Antigen Receptors
Acute Myeloid Leukemia
Leukemia
Phenotype
1 Citations

Anti-correlated cortical networks arise from spontaneous neuronal dynamics at slow timescales

Kodama, N. X., Feng, T., Ullett, J. J., Chiel, H., Sivakumar, S. S. & Galan, R. F., Dec 1 2018, In : Scientific Reports. 8, 1, 666.

Research output: Contribution to journalArticle

Somatosensory Cortex
Microelectrodes
Cerebral Cortex

Antidiabetic treatment patterns and specialty care utilization among patients with type 2 diabetes and cardiovascular disease

Pantalone, K., Misra-Hebert, A. D., Hobbs, T. M., Ji, X., Kong, S. X., Milinovich, A., Weng, W., Bauman, J., Ganguly, R., Burguera, B., Kattan, M. W. & Zimmerman, R. S., Apr 10 2018, In : Cardiovascular Diabetology. 17, 1, 54.

Research output: Contribution to journalArticle

Hypoglycemic Agents
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Therapeutics
Diabetes Complications

Antimicrobial Stewardship in Long-Term Care Facilities: Approaches to Creating an Antibiogram when Few Bacterial Isolates Are Cultured Annually

Tolg, M. S. A., Dosa, D. M., Jump, R. L., Liappis, A. P. & LaPlante, K. L., Jan 1 2018, (Accepted/In press) In : Journal of the American Medical Directors Association.

Research output: Contribution to journalArticle

Microbial Sensitivity Tests
Long-Term Care
Centers for Medicare and Medicaid Services (U.S.)
Proxy
Centers for Disease Control and Prevention (U.S.)
1 Citations

Anti-sema3a antibody: A novel therapeutic agent to suppress glioblastoma tumor growth

Lee, J., Shin, Y. J., Lee, K., Cho, H. J., Sa, J. K., Lee, S. Y., Kim, S. H., Lee, J., Yoon, Y. & Nam, D. H., Jul 1 2018, In : Cancer Research and Treatment. 50, 3, p. 1009-1022 14 p.

Research output: Contribution to journalArticle

Semaphorin-3A
Glioblastoma
Anti-Idiotypic Antibodies
Growth
Neoplasms
2 Citations

An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein

Glidden, M. D., Aldabbagh, K., Phillips, N. F. B., Carr, K., Chen, Y. S., Whittaker, J., Phillips, M., Wickramasinghe, N. P., Rege, N., Swain, M., Peng, Y., Yang, Y., Lawrence, M. C., Yee, V., Ismail-Beigi, F. & Weiss, M. A., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 47-68 22 p.

Research output: Contribution to journalArticle

Hot Temperature
Insulin
Proteins
Cell signaling
Refrigeration