A 68-Year-Old Man With Chronic Myelogenous Leukemia and a Large Unilateral Pleural Effusion

Adam Alter, Neal Chaisson, Sudipto Mukherjee, Thomas Gildea

Research output: Contribution to journalArticle

Abstract

Case Presentation: A 68-year-old man with chronic myelogenous leukemia presents for evaluation of 2 months of dyspnea with exertion. He denies cough, fever, chest pain, weight gain, orthopnea, and edema. Since diagnosis of chronic myelogenous leukemia 5 years ago, he has been treated with dasatinib, with recent BCR-ABL1 assay showing no detectable disease in the peripheral blood. Medical history also includes hyperlipidemia, prostate enlargement, and hypothyroidism, but no prior heart or lung disease. Born in the Middle East, he immigrated to the United States 30 years ago and is working as a physician. He received the Bacillus Calmette–Guérin vaccine as a child. Quantiferon Gold test 1 year ago was positive (TB antigen response 0.91, reference range in <0.35), but he has not received treatment for this. He is a lifelong nonsmoker and rarely drinks alcohol. Medications include dasatinib, rosuvastatin, levothyroxine, tamsulosin, and dutasteride.

LanguageEnglish (US)
Pages339-348
Number of pages10
JournalCHEST
Volume153
Issue number2
DOIs
StatePublished - Feb 1 2018

Fingerprint

tamsulosin
Pleural Effusion
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
BCG Vaccine
Middle East
Hypothyroidism
Hyperlipidemias
Chest Pain
Thyroxine
Cough
Gold
Dyspnea
Lung Diseases
Weight Gain
Prostate
Heart Diseases
Edema
Reference Values
Fever
Alcohols

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

A 68-Year-Old Man With Chronic Myelogenous Leukemia and a Large Unilateral Pleural Effusion. / Alter, Adam; Chaisson, Neal; Mukherjee, Sudipto; Gildea, Thomas.

In: CHEST, Vol. 153, No. 2, 01.02.2018, p. 339-348.

Research output: Contribution to journalArticle

Alter, Adam ; Chaisson, Neal ; Mukherjee, Sudipto ; Gildea, Thomas. / A 68-Year-Old Man With Chronic Myelogenous Leukemia and a Large Unilateral Pleural Effusion. In: CHEST. 2018 ; Vol. 153, No. 2. pp. 339-348.
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