Model-based analysis of spinal cord stimulation for chronic pain

Scott F. Lempka, Hans Zander, Carlos J. Anaya, Alexandria Wyant, John G. Ozinga, Andre G Machado

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Spinal cord stimulation (SCS) is a widely-used therapy for chronic pain management. Computational models provide a valuable tool to study the effects of SCS on the nervous system. However, it is critical that these models include sufficient detail to correlate model predictions with clinical effects, including patient-specific data. Therefore, in this study, we developed a patient-specific computer model for a patient undergoing SCS to treat neuropathic pain. The patient-specific model predicted sensory threshold estimates that were consistent with the corresponding clinical measurements. These results demonstrate the potential for patient-specific computer models to quantitatively describe the axonal response to SCS and to address scientific questions related to clinical SCS.

LanguageEnglish (US)
Title of host publicationBiosystems and Biorobotics
PublisherSpringer International Publishing
Pages39-43
Number of pages5
DOIs
StatePublished - Jan 1 2019

Publication series

NameBiosystems and Biorobotics
Volume21
ISSN (Print)2195-3562
ISSN (Electronic)2195-3570

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Neurology

ASJC Scopus subject areas

  • Biomedical Engineering
  • Mechanical Engineering
  • Artificial Intelligence

Cite this

Lempka, S. F., Zander, H., Anaya, C. J., Wyant, A., Ozinga, J. G., & Machado, A. G. (2019). Model-based analysis of spinal cord stimulation for chronic pain. In Biosystems and Biorobotics (pp. 39-43). (Biosystems and Biorobotics; Vol. 21). Springer International Publishing. https://doi.org/10.1007/978-3-030-01845-0_8

Model-based analysis of spinal cord stimulation for chronic pain. / Lempka, Scott F.; Zander, Hans; Anaya, Carlos J.; Wyant, Alexandria; Ozinga, John G.; Machado, Andre G.

Biosystems and Biorobotics. Springer International Publishing, 2019. p. 39-43 (Biosystems and Biorobotics; Vol. 21).

Research output: Chapter in Book/Report/Conference proceedingChapter

Lempka, SF, Zander, H, Anaya, CJ, Wyant, A, Ozinga, JG & Machado, AG 2019, Model-based analysis of spinal cord stimulation for chronic pain. in Biosystems and Biorobotics. Biosystems and Biorobotics, vol. 21, Springer International Publishing, pp. 39-43. https://doi.org/10.1007/978-3-030-01845-0_8
Lempka SF, Zander H, Anaya CJ, Wyant A, Ozinga JG, Machado AG. Model-based analysis of spinal cord stimulation for chronic pain. In Biosystems and Biorobotics. Springer International Publishing. 2019. p. 39-43. (Biosystems and Biorobotics). https://doi.org/10.1007/978-3-030-01845-0_8
Lempka, Scott F. ; Zander, Hans ; Anaya, Carlos J. ; Wyant, Alexandria ; Ozinga, John G. ; Machado, Andre G. / Model-based analysis of spinal cord stimulation for chronic pain. Biosystems and Biorobotics. Springer International Publishing, 2019. pp. 39-43 (Biosystems and Biorobotics).
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