Sleep architecture in adults with epilepsy: a systematic review

Pedro Sudbrack-Oliveira, Lucas Lima Najar, Nancy Foldvary-Schaefer, Marleide da Mota Gomes

Research output: Contribution to journalReview article

Abstract

Objectives: To assess whether sleep architecture differs in subgroups of adults with epilepsy or in adults with epilepsy compared to control populations. Methods: We completed a systematic review of papers published in two databases up to May 2018, with adults with epilepsy who have undergone either two consecutive nights of in-laboratory polysomnography (PSG) or one night of ambulatory PSG. Our review followed the PRISMA statements and guidelines and the protocol was registered in the PROSPERO platform prior to initiation of the review process (record CRD42018084009). Results: Five studies out of 872 fulfilled our eligibility criteria. Only one study reported a significant difference in any sleep architecture parameter in group comparisons. Crespel et al., found that wake after sleep onset (WASO) time in minutes was higher in patients with refractory temporal lobe epilepsy when compared to refractory frontal lobe epilepsy (78.2 ± 5.3 vs. 28.1 ± 2.2; p < 0.01) and healthy controls (78.2 ± 5.3 vs. 27.9 ± 18.9; p < 0.007). Conclusions: Only a few studies objectively assessed sleep in adults with epilepsy while controlling for key factors that influence sleep. However, even those reports are heterogeneous in regards to methodology and population characteristics. Further studies are required to access the extent of sleep architectural abnormalities in adults with epilepsy.

LanguageEnglish (US)
Pages22-27
Number of pages6
JournalSleep medicine
Volume53
DOIs
StatePublished - Jan 1 2019

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REM Sleep
Epilepsy
Sleep
Polysomnography
Frontal Lobe Epilepsy
Temporal Lobe Epilepsy
Population Characteristics
Databases
Guidelines
Population

Keywords

  • Epilepsy
  • Hypnogram
  • NREM sleep
  • REM sleep
  • Sleep architecture

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sleep architecture in adults with epilepsy : a systematic review. / Sudbrack-Oliveira, Pedro; Lima Najar, Lucas; Foldvary-Schaefer, Nancy; da Mota Gomes, Marleide.

In: Sleep medicine, Vol. 53, 01.01.2019, p. 22-27.

Research output: Contribution to journalReview article

Sudbrack-Oliveira, Pedro ; Lima Najar, Lucas ; Foldvary-Schaefer, Nancy ; da Mota Gomes, Marleide. / Sleep architecture in adults with epilepsy : a systematic review. In: Sleep medicine. 2019 ; Vol. 53. pp. 22-27.
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